Laboratories continues to have RaySearch and ADAC Laboratories close clinical ties to Karolinska Announce Collaboration to Develop and is now actively commercializing Next Generation of Radiation the results of this collaboration. Therapy Planning Software for Cancer Treatment. David Crussell, vice president and general manager of ADAC's Radiation July 25, 2000 Therapy Product business, stated, "Our Pinnacle product has achieved RaySearch Laboratories and ADAC its market-leading position by Laboratories (Nasdaq: ADAC) providing superior software tools announced today at the annual that bring advanced techniques into American Association of Physicists clinical practice. Including in Medicine meeting, a multi-year ORBIT's biological optimization exclusive agreement with RaySearch capability will provide radiation Laboratories AB, based in oncology departments with the next Stockholm, Sweden, to jointly generation of advanced inverse IMRT develop the next generation inverse planning on the Pinnacle platform. planning intensity-modulated We are delighted to work with our radiation therapy (IMRT) software long-term technology partner, that will be integrated with ADAC's RaySearch, to bring this valuable Pinnacle3 3D radiation treatment technology into the market." planning system. Johan Löf, director of product The new software will be based on development at RaySearch, noted the ORBIT (Optimization of Radiation synergy between ORBIT and ADAC's Therapy Beams by Iterative Pinnacle3 system. "We are excited Technique), an advanced software to work with ADAC to combine into a tool developed at the Karolinska single, integrated package ORBIT's Institute in Stockholm that is used ability to optimize radiation to optimize radiation therapy therapy treatment plans with the planning for the treatment of clinical accuracy of Pinnacle3's cancer. SmartSim CT simulation software and dose calculation algorithms. We ORBIT represents a clinical believe the combined system will be breakthrough in inverse planning the most clinically usable and IMRT technology because it is relevant product available for capable of handling very complex intensity modulation treatment problems, such as the simultaneous planning." optimization of intensity modulation and radiation beam "ORBIT provides another logical directions, using both physical and extension to our IMRT treatment biological treatment objectives. As planning capabilities," said Harry a result, ORBIT provides physicians Tschopik, director of global the potential to be both more marketing for ADAC's Radiation precise and more aggressive than Therapy Products group. "ADAC's current IMRT treatments. It enables Pinnacle3 has been the dominant the radiation oncologist to design market leader in conformal an optimal treatment plan to radiation therapy planning over the achieve complication-free tumor last several years. IMRT is an control while accounting for extension of conformal therapy and treatment uncertainties due to many of our users perform forward organ motion, treatment setup planning IMRT using Pinnacle's errors, and variations in patient current software. The inverse sensitivity to radiation therapy. planning IMRT software we are now developing will allow Pinnacle to ORBIT has been under development as determine an optimal plan based on a research tool at the Karolinska user-defined physical objectives. Institute since 1985 and at With ORBIT, physicians will finally RaySearch Laboratories since 2000. be able to take into account In 1997, ADAC became a collaborator biological as well as physical with medical physicists from factors during plan optimization. Karolinska on the further We are very excited about the development of ORBIT. RaySearch potential of these new tools for improving cancer treatments and the positive impact this will have on our business going forward." This news release contains forward- looking statements, including statements concerning For further information please contact: Johan Löf, RaySearch Laboratories Tel: + 46 8-545 061 30, e-mail: Johan.lof@raysearchlabs.com About RaySearch Laboratories RaySearch Laboratories is a company based in Stockholm, Sweden. RaySearch is committed to delivering innovative methods and software for the improvement of radiation therapy. The company bases its operation on decades of pioneering research in the field of radiation therapy optimization performed at the Karolinska Institute in Stockholm. About ADAC Laboratories ADAC Laboratories is the world market-share leader in nuclear medicine and radiation therapy planning systems, and a technology leader providing clinical workflow solutions, management information and knowledge systems to healthcare organizations in North America. ADAC is headquartered in Milpitas, CA, and its HealthCare Information Systems Division is located in Houston, Texas. ------------------------------------------------------------ This information was brought to you by Waymaker http://www.waymaker.net The following files are available for download: http://www.waymaker.net/bitonline/2004/02/06/20040206BIT00390/wkr0001.doc http://www.waymaker.net/bitonline/2004/02/06/20040206BIT00390/wkr0002.pdf
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