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Future-proof proton treatment planning with RayStation

Proton therapy is a highly precise treatment method. As such, it is also sensitive to change. Advanced treatment planning system RayStation is designed to account for every eventuality.

Unrivaled capabilities

RayStation supports proton therapy systems from many leading manufacturers as well as synchrotrons. It offers the full range of treatment options, including pencil-beam scanning, double scattering, uniform scanning, line scanning and wobbling.

Unique features that RayStation is renowned for are also available for proton therapy.

Highlights include:

  • Fast Monte Carlo dose computation/optimization
  • Robust optimization and evaluation
  • 4D optimization
  • Multi-criteria optimization with robustness
  • PBS optimization with apertures
  • Fully integrated adaptive planning
  • Simulated organ motion
  • Interplay evaluation
  • Automatic creation of backup photon plans

Top choice worldwide

Proton therapy centers around the world rely on the advanced capabilities and high speed of RayStation. The system has been adopted by over 50 particle centers in 18 countries.

Watch a presentation from PTCOG

A comprehensive approach to lung treatment. In this first tutorial, you will get a general introduction to adaptive radiation therapy and on how to perform dose tracking in RayStation.

RayStation provides clinicians with tools for designing and optimizing actively scanned pencil beams – including IMPT – single-field uniform dose and distal-edge tracking with the option to include block apertures or MLC collimation.

Spot weight limits are included in the optimization loop, so all optimized plans are directly deliverable.

Aperture shape can be created using treat-and-protect ROI with user-defined margins. Manual tools can then be used to shape and edit. Accurate dose computation is achieved using the Monte Carlo dose engine, including the block edge scattering effect. Block aperture is considered in spot selection and included in dose calculation for optimization (pencil beam or Monte Carlo).

  • Fast Monte Carlo dose engine for optimization and final dose
  • Pencil beam dose engine
  • Optimization of pencil beam scanning and line scanning using multi-field optimization and single field uniform dose techniques.
  • Robust optimization of over multiple 4D-CT images, scenario-based optimization regarding uncertainties in range (density) and position (including isocenter shifts and target shifts)
  • Control of initial energy layer and spot selection per beam with respect to target and OAR
  • Layer repainting
  • Range shifter support
  • Bragg peak visualization

PBS-specific features:

  • Step-and-shoot spot scanning
  • Optimization including lower and upper limits of spot MU delivery
  • Spot visualization with beam’s-eye-view and patient 2D/3D views
  • Manual editing of spot pattern
  • Spot weight filtering
  • Quasi-discrete PBS
  • Spot order sorting through scan path length optimization

Line scanning specific features:
  • Line segment visualization
  • Line segment filtering in optimization with beam’s-eye-view and patient 2D/3D views

Watch an introduction video to proton PBS in RayStation.

Watch a video about advanced proton planning in RayStation.

RayStation features a fast Monte Carlo dose engine for proton pencil beam scanning (PBS) plans, which can be used for final dose computation and optimization.

The Monte Carlo technique is based on simulating the transport of individual particles, which makes it possible to fully account for the unaltered patient geometry. The dose engine in RayStation strikes the optimal balance between accurate physics modeling and speed, making it highly effective in clinical workflows.

The Monte Carlo and pencil beam dose engines in RayStation are designed to be used in parallel, ensuring efficient and accurate dose calculation for all proton PBS planning needs. A single PBS machine model for a particular delivery system can support both the Monte Carlo and pencil beam dose calculations, and the beam-measurement data needed for commissioning is the same for both dose engines.

The Monte Carlo and pencil beam dose engines can both be used for calculating spot dose distributions as input for optimization, with or without patient-specific block apertures, as well as for calculating a final dose distribution for plan approval.   

  • Computation of final dose
  • Computation of dose for optimization
  • Termination criterion for final dose computation in the plan optimization module defined by statistical uncertainty level, or by number of simulated protons
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Simulated organ motion

The ability to simulate organ motion in RayStation strengthens the functionality of robust planning and plan evaluation even further. With the ability to generate simulated images for organ motion, the full effect of the changing anatomy can be evaluated without the need of acquiring multiple patient CT scans.

Sets of deformed images are generated based on motion expectation for user-selected ROI. The organ motion will affect the overall patient anatomy in cooperation with specified fixed areas. The generated group of motion image sets can be used for both evaluation and as input when planning robustly against intra-fractional or inter-fractional organ motion.

The RayStation® treatment planning system is specifically designed to make adaptive therapy faster and easier in clinical practice. It includes modules for dose tracking and adaptive re-planning.

We are also developing, in collaboration with IBA, an online adaptive workflow solution* where daily cone beam images are taken and matched to the planning CT for a particular patient. Based on the daily images, an updated treatment plan can be automatically suggested to the care team at the time of a treatment session. A plan adaptation that takes the patient’s current situation into account can thus be made before treatment delivery starts. This workflow benefits patients by allowing for more accurate treatments and faster plan adaptation.

*Subject to regulatory clearance in some markets.


Because RayStation is a complete treatment planning system that supports many different modalities, planning of proton treatments in conjunction with photons is possible. The fallback planning module also enables proton plans to be converted into photon plans, ensuring there is no interruption in treatment.

Provision Center for Proton Therapy

See how Provision Center for Proton Therapy achieve great results in Proton PBS with RayStation.