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Proton therapy is a highly precise treatment method, which also makes it sensitive to change. RaySearch understands this, and we’ve designed the RayStation treatment planning system to account for every eventuality.

Unmatched capabilities

RayStation supports proton therapy systems from IBA, Mitsubishi, Mevion, Varian and Sumitomo, as well as synchrotrons. The system offers the full range of treatment options, including pencil beam scanning, double scattering, uniform scanning, line scanning and wobbling.

The unique features that RayStation is renowned for are also available for proton therapy. Highlights include.

  • Monte Carlo dose computation
  • Robust and 4D optimization,
  • PBS optimization with apertures
  • Multi-criteria optimization
  • Fully integrated adaptive planning
  • Automatic creation of backup photon plans


The top choice worldwide

Proton therapy centers around the world rely on RayStation’s advanced capabilities and high speed. The system has been adopted by 29 proton centers in 13 countries.

Proton planning with RayStation

Whatever your goals in proton therapy, RayStation has the capabilities you need. It supports a variety of treatment techniques and beam lines and also includes a Monte Carlo dose engine for pencil beam scanning plans, bringing an additional level of precision without compromising on speed.

RayStation utilizes a unique robust optimization method that takes the effects of potential changes into account from the outset and makes your plan robust even against a worst case scenario. Other issues include interfractional motion resulting in interplay effects, and RayStation offers tools to evaluate and mitigate these. Additionally, RayStation’s unique capabilities for adaptive therapy, such as its efficient replanning tools, can help you control the course of the treatment even under the influence of change. 

Highly compatible, RayStation is the go-to choice for centers that need a single treatment planning system for proton systems from multiple vendors, including IBA, Varian, Mevion, Mitsubishi Electric and Sumitomo.



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Monte Carlo dose calculation

RayStation 6 introduces a Monte Carlo dose engine for proton pencil beam scanning (PBS) plans, which can be used in parallel with the existing pencil beam dose engine.

The Monte Carlo technique is based on simulating the transport of individual particles, which makes it possible to fully account for the unaltered patient geometry. The dose engine in RayStation strikes the optimal balance between accurate physics modeling and speed, making it highly effective in clinical workflows.

The Monte Carlo and pencil beam dose engines in RayStation are designed to be used in parallel, ensuring efficient and accurate dose calculation for all proton PBS planning needs. A single PBS machine model for a particular delivery system can support both the Monte Carlo and pencil beam dose calculations, and the beam-measurement data needed for commissioning is the same for both dose engines.

The Monte Carlo and pencil beam dose engines can both be used for calculating spot dose distributions as input for optimization, with or without patient-specific block apertures, as well as for calculating a final dose distribution for plan approval.

  • Computation of final dose
  • Computation of dose for optimization
  • Termination criterion for final dose computation in the Plan Optimization module defined by statistical uncertainty level, or by number of simulated protons
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Proton Pencil Beam Scanning planning/ rayPencilScanning and rayLineScanning

RayStation provides leading tools for designing and optimizing actively scanned pencil beam proton treatment plans, including IMPT, single field uniform dose and distal edge tracking.

RayStation enables design and optimization of proton treatment plans for actively scanned pencil beams, with the option to include block apertures. All optimized plans are directly deliverable since the spot weight limits are taken into account in the optimization loop.

Aperture shape can be created using treat-and-protect ROI with user-defined margins, and manual tools can be used to shape and edit. Accurate dose computation is achieved using the Monte Carlo dose engine, including the block edge scattering effect. Block aperture is taken into account in spot selection and included in dose calculation for optimization (pencil beam or Monte Carlo).

A wide selection of tools for robust optimization makes it possible to create treatment plans that are robust to geometrical and dosimetric uncertainties.In addition, the inclusion of 4D-CT images in the robust optimization process addresses situations where there is significant relative interfractional motion of internal organs, such as in the thorax during free breathing. 

Other challenges arising from intrafractional motion include interplay effects, which will occur if the delivery takes place on a similar time scale as the intrafractional organ motion. Evaluation of these effects and methods to mitigate them is crucial, and RaySearch has developed tools for this purpose, such as layer repainting. All plans are directly deliverable after optimization since the minimum spot weight is taken into account in the optimization.

  • Ultrafast Monte Carlo dose engine for optimization and final dose
  • Pencil beam dose engine
  • PBS treatments with block apertures 
  • Optimization of pencil beam scanning and line scanning using multi-field optimization and single field uniform dose techniques.
  • 4D optimization
  • Robust optimization over multiple 4D-CT images, scenario-based optimization regarding uncertainties in range (density) and position (isocenter shifts, target shifts, etc.)
  • Control of initial energy layer and spot selection per beam with respect to target and OAR
  • Layer repainting
  • Range shifter support
  • Bragg peak visualization

PBS specific features:

  • Step-and-shoot spot scanning
  • Optimization including lower and upper limits of spot MU delivery
  • Spot visualization with beam’s-eye-view and patient 2D/3D views
  • Manual editing of spot pattern
  • Spot weight filtering
  • Quasi-discrete PBS
  • Spot order sorting through scan path length optimization

Line scanning specific features:

  • Line segment visualization
  • Line segment filtering in optimization with beam’s-eye-view and patient 2D/3D views


Watch how Provision manages its proton planning with RayStation

Provision Center for Proton Therapy in Knoxville, Tennessee, was the first proton center to use RayStation for their proton treatments. They are treating with the most advanced form, Pencil Beam Scanning. See the great results they achieve with RayStation!

Watch introduction video to proton PBS in RayStation

Watch video on advanced proton planning in RayStation

Conformal proton planning/ rayPassiveScattering, rayUniformScanning and rayWobbling

rayPassiveScattering, rayUniformScanning and rayWobbling provide modern tools for efficient planning of uniform scanning, double scattering and Sumitomo wobbling.

rayUniformScanning, rayPassiveScattering and rayWobbling help the user create clinical treatment plans and subsequent milling machine instructions including the automated creation of compensators and blocks with manual editing possibilities. 

  • Support for beam delivery techniques using continuous as well as fixed SOBP modulation width
  • Automatic and/or manual selection of:
    - SOBP field range and width
    - nominal beam energy and ridge filter setting
  • Block aperture computation
  • Beam specific target and risk organ specification
  • Border smoothing taking the milling tool size into account
  • Aperture shape exported via DICOM
  • Compensator computation
  • Conforms to beam specific targets and distal blocking ROIs
  • Smearing and maximum gradient filters
  • Milling/drilling tool size taken into account
  • Compensator shape exported via DICOM
  • Versatile tools for manual editing of exit aperture, compensator and MLC shape
  • Patch fields and feathering tools
  • Beam weighting using sliders