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Revolutionize treatment planning with speed and smart optimization

We think plan quality relies on smart optimization and fast calculation speed, two fundamental aspects of RayStation. Did you for example know that by using more intelligent software optimization you can decrease delivery time with no sacrifice in treatment plan quality without upgrading or replacing your current linacs? That calculation speed is key to the quality of your plans?

Ultrafast computation speed

With RayStation, you benefit from unrivaled computation speed that should radically transform your treatment planning process.

As the computation time is measured in seconds rather than minutes, you can efficiently produce several competing treatment plans to assess different trade-off situations instead of opening a second case or going on a break during computations.

Optimization and clinical dose computation for a standard prostate IMRT case is done in less than ten seconds and in approximately 30 seconds for a more complex 9-beam IMRT head and neck case on a high resolution 2mm dose grid.*

Depending on the modality, RayStation uses different beam models and dose calculation engines to quickly and accurately calculate dose. In the latest release CC-dose algorithms have been rewritten for CPU and GPU to further speed up dose computation.

*results may vary as dose computation time depends on several variables.

Watch demonstration

The effect of planning speed on VMAT plan quality
Decreasing calculation times for VMAT planning from around 10-17 min for optimization and final dose calculation to around 2 – 4 minutes significantly increased the fulfillment of clinical goals.
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Smart core optimization/ rayOptimizer

RayStation includes an ultrafast multi-purpose optimization engine that can solve virtually any posed optimization problem within radiation therapy regardless of beam modality and treatment technique.

rayOptimizer contains the generic optimization engine used for all plan optimization, irrespective of beam modality and treatment technique. The optimization method used is called sequential quadratic programming and allows for efficient optimization of a non-linear objective, non-linear constraints and rigorous handling of linear constraints and bounds. For convex functions, it guarantees convergence to the globally optimal solution.

  • Multi-purpose optimization engine.
  • Robust optimization based on density and patient setup uncertainties.
  • Physical objective and constraint functions, such as min/max dose, min/max DVH, min/max EUD, uniform dose and target conformance.
  • Templates for objectives and constraints.
  • Automatic dose improvements.


Reduce Organ At Risk Dose

Reduce Organ At Risk Dose enables treatment planners to consistently reach plans that cannot be improved upon.

Reduce Organ At Risk Dose is a one-click post-processing functionality in RayStation that can easily be applied after conventional planning whenever Continue optimization can. It enables treatment planners to consistently reach plans that cannot be improved upon.

Treatment planning is typically performed towards fulfillment of a set of clinical goals. Once a plan satisfying the clinical goals has been found, there are often aspects of the plan that can be further improved upon. To simplify procuring the improvements, RayStation implements the Reduce Organ at Risk (OAR) dose functionality, which uses the current plan as a reference and aims to improve upon the treatment plan without compromising any goal. Reduce OAR dose automatically reduces the OAR doses as much as possible while the dose distributions of all targets and OARs are constrained not to deteriorate compared to the reference plan. 

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Radiobiological optimization and evaluation/ rayBiology

The use of radiobiological response models brings the planning process closer to the intent to create a plan with the highest possible probability of curing the patient while keeping the risk of complications to the surrounding healthy tissue as low as possible. The philosophy is to use the biological models to reveal effects that are difficult to understand from the dose distribution alone.

rayBiology provides tools for both biological optimization and evaluation.

Optimization tools provide the ability to optimize directly on the biological indices in combination with physical dose indices. It makes it possible to configure optimization problems which more closely describe the clinical intentions, such as minimizing normal tissue complication probabilities subject to a guaranteed homogenous target dose within a specified standard deviation.

Evaluation tools includes Tumor Control Probability (TCP) and Normal Tissue Complication Probability (NTCP) models which can be combined with tissue repair and tumor growth models. The biological tools are integrated in the plan evaluation module. That way the physical properties of the existing plan can easily be investigated if unexpected differences in the biological response are observed between different plans. In addition there is a Biological Evaluation module dedicated to the exploration of the biological effects of altering the fractionation schedule of a single treatment plan.

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Boost your linac with smart optimization

With RayStation, you can take constant dose rate VMAT to the next level thanks to smart optimization. You can reach plan quality equivalent to variable dose rate VMAT without an expensive hardware upgrade.

Using modern and innovative treatment planning tools, it is possible to create deliverable SCDR plans with comparable plan quality as corresponding VDR plans, without upgrading the linac to VDR. The delivery times of both the VDR and the SCDR plans are significantly shorter than what is reported for IMRT plans. The mean delivery times of the tested prostate plans are between 1 and 2 minutes for both techniques, and between 2 and 4 minutes for the tested head and neck plans.

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